Which vaccines are recommended during pregnancy to protect the newborn?

• A. No vaccines during pregnancy.
• B. Influenza vaccine for all pregnant people; Tdap in the third trimester.
• C. MMR vaccine during pregnancy.
• D. Varicella vaccine during pregnancy.

Answer: (B)

Maternal immunization aims to protect newborns by passing antibodies from mother to baby. The strongest, well-supported approach during pregnancy is to give inactivated vaccines that are safe for the fetus and can transfer protective antibodies.

The influenza vaccine is recommended for all pregnant people because flu can be more severe during pregnancy, and vaccination protects both mother and baby by reducing maternal illness and hospitalization, with added partial protection to the newborn after birth. In addition, a dose of Tdap during the third trimester is advised to boost antibodies against tetanus, diphtheria, and pertussis; these antibodies cross the placenta and help shield the newborn during the first months of life when pertussis can be most dangerous and the baby isn’t yet eligible for routine vaccination.

Live vaccines such as MMR and varicella are not given during pregnancy due to potential risks to the fetus. They are typically administered after delivery if needed.